Purpose

Trial for patients on one or no medications with SBP 150-180 mmHg - this trial is designed to see if renal denervation can be used as a primary option for hypertension (HTN).

Follow up: Patients in the SPYRAL HTN-OFF MED study will be followed every 2 weeks for 3 months then at 6, 12, 24, and 36 months.

Renal Denervation: The procedure is called renal denervation, which uses a medical device catheter to deliver low-level radiofrequency (RF) energy through the wall of a blood vessel (renal artery) to the kidney.  This procedure may decrease the kidneys’ release of hormones that raises the blood pressure, which may in turn decrease high blood pressure.