Sodium Nitroprusside for Blood Pressure Reduction in the ICU (SNP2)

Trial ID or NCT#

NCT00621816

Status

not recruiting iconNOT RECRUITING

Purpose

Nitroprusside is used commonly in the Intensive Care Unit for long periods of time in order to reduce blood pressure. It is not known if the body compensates over time to the blood pressure lowering, and if when the nitroprusside is stopped the blood pressure goes up at a faster rate and is higher than it was at the start of the treatment. This study will answer these questions.

Official Title

A Phase 2, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel Group Study to Determine the Pharmacodynamics of Sodium Nitroprusside During Prolonged Infusion in Pediatric Subjects

Eligibility Criteria

Ages Eligible for Study: 1 Day to 17 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No

Investigator(s)

Gregory Hammer