Study of Drug Concentration of Ondansetron and Cefazolin in Mothers and Neonates
Trial ID or NCT#
Status
Purpose
This study proposes to look at the pharmacokinetics of two drugs (Cefazolin and ondansetron) given routinely to pregnant women who are planning to deliver via cesarean section. The investigators will evaluate the metabolism of both drugs by the pregnant woman, the placental transfer over time, and the subsequent metabolism of the transferred drug in the neonate.
Official Title
Pharmacokinetics and Placental Transfer of Ondansetron and Cefazolin: A Preliminary Analysis
Eligibility Criteria
- Adult participant: - Age 18-45 years old - Term pregnancy (37-42 weeks) - Delivers by planned cesarean section, or unplanned, non-urgent cesarean section. - Generally healthy - Able and willing to sign informed consent Neonatal participant: - Male of female - 37-42 weeks gestation
- - Adult:Medical condition that would effect metabolism of the study drugs - Known allergy to either study medication - Use of medications in the last 48 hours that might induce or inhibit metabolism of ondansetron (e.g. barbiturates, fluconazole, erythromycin, etc.)
Contact us to find out if this trial is right for you.
Contact
Martha Tingle
6507242742
View on ClinicalTrials.gov