The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)

Trial ID or NCT#

NCT03882788

Status

not recruiting iconNOT RECRUITING

Purpose

The purpose of this study is to assess whether the type of anesthesia, narcotic-based versus inhalational anesthesia administered during cardiopulmonary bypass (CPB) surgery contributes to the wide variation in neurologic recovery and developmental outcome after surgery in infants with congenital heart disease.

Official Title

Anesthesia and the Developing Brain: a Comparison of Two Anesthetic Techniques

Eligibility Criteria

Ages Eligible for Study: 1 Day to 36 Months
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - Neonates of at least 32 weeks of gestation, infants and children up to 2 years of age admitted to The Children's Hospital for treatment of cyanotic or non-cyanotic heart disease requiring surgical intervention. - Admitting diagnosis of cyanotic or non-cyanotic heart disease
Exclusion Criteria:
  1. - Neonates less than 32 weeks of gestational age, and children more than 2 years of age. - Any documented central nervous system malformations. - Any potential subject requiring unexpected postoperative Extracorporeal membrane oxygenation (ECMO) support

Investigator(s)

Lisa Wise-Faberowski