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Reply to: "The decreasing predictive power of MELD in an era of changing etiology of liver disease". American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons Kwong, A., Mannalithara, A., Kim, W. R. 2019

Abstract

We read with interest the recent article by Godfrey et al.(1) regarding the predictive power of the Model for End-Stage Liver Disease (MELD), the score used for allocation of donor livers, over time. The authors report that the discriminative ability of MELD for the prediction of 90-day waitlist mortality, as measured by the concordance statistic (c-statistic), had declined from 0.80 in 2002 to 0.70in 2015 among new waitlist registrants. These values are inconsistent with previously published estimates.

View details for DOI 10.1111/ajt.15733

View details for PubMedID 31814299