5-Day Preoperative Radiation for Soft Tissue Sarcoma
Trial ID or NCT#
NCT06087861
Status
RECRUITING
Purpose
The purpose of this study is to examine the safety and efficacy of an abbreviated course of preoperative radiation, given over five days, for patients with soft tissue sarcoma of the extremity, trunk or retroperitoneum. This is in contrast to standard preoperative radiation, which is given over 25 days.
Official Title
Phase 2 5-Day Preoperative Radiation for Soft Tissue Sarcoma
Eligibility Criteria
Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
- 1. Histologically confirmed soft tissue sarcoma of the extremity, trunk or retroperitoneum. 2. Has been offered preoperative radiation and surgery as part of standard-of-care treatment 3. Age ≥ 18 4. KPS ≥ 70 or ECOG 0 to 2 5. Life expectancy ≥ 6 months 6. If a woman is of childbearing potential, a negative serum or urine pregnancy test must be documented. 7. Ability to understand and the willingness to personally sign the written IRB approved informed consent document.
Exclusion Criteria:
- 1. History of prior radiation to the area to be treated. 2. Active use of other anti-cancer investigational agents. 3. Planned use of concurrent chemotherapy, targeted therapy, or immunotherapy with radiation therapy (defined as the time interval starting 1 week before the first and last fraction of radiation therapy and surgery). 4. Pregnancy.
Investigator(s)
Everett J. Moding, MD, PhD
Radiation oncologist
Assistant Professor of Radiation Oncology (Radiation Therapy)
Contact us to find out if this trial is right for you.
Contact
Jillian Skerchak
650-721-4072
View on ClinicalTrials.gov
