68Ga-PSMA PET/CT or PET/MRI in Evaluating Patients With Recurrent Prostate Cancer

Trial ID or NCT#



not recruiting iconNOT RECRUITING


This clinical trial studies gallium-68 (68Ga)-prostate specific membrane antigen (PSMA) (gallium Ga 68-labeled PSMA ligand Glu-urea-Lys\[Ahx\]) positron emission tomography (PET)/computed tomography (CT) or PET/magnetic resonance imaging (MRI) in identifying prostate cancer that may have returned after a period of improvement (biochemical recurrence). 68Ga-PSMA is a radiopharmaceutical that localizes to a specific prostate cancer receptor, which can then be imaged by the PET/CT or PET/MRI scanner.

Official Title

68Ga-PSMA PET/CT or PET/MRI in the Evaluation of Patients With Prostate Cancer: A Feasibility Study

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: MALE
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. * Provides written informed consent* Known diagnosis of prostate cancer* Patient has suspected recurrence based on biochemical data (prostate specific antigen \[PSA\] \> 2 ng/mL)* Able to remain still for duration of each imaging procedure (about one hour)
Exclusion Criteria:
  1. * Unable to provide informed consent* Inability to lie still for the entire imaging time* Inability to complete the needed investigational and standard-of-care imaging examinations due to other reasons (severe claustrophobia, radiation phobia, etc.)* Any additional medical condition, serious intercurrent illness, or other extenuating circumstance that, in the opinion of the Investigator, may significantly interfere with study compliance


Geoffrey Sonn
Geoffrey Sonn
Urologic oncologist, Urologist, Urologic specialist, Genitourinary specialist, Urologic surgeon
Associate Professor of Urology and, by courtesy, of Radiology (Body MRI)
Andreas Loening
Andreas Loening
Diagnostic radiologist, Radiologist
Assistant Professor of Radiology (Body MRI)
Sandy Srinivas
Sandy Srinivas
Medical oncologist, Urologic specialist, Genitourinary specialist
Professor of Medicine (Oncology) and, by courtesy, of Urology
Andrei Iagaru
Andrei Iagaru
Professor of Radiology (Nuclear Medicine)

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