68Ga-PSMA PET/CT in Detecting Prostate Cancer Recurrence in Patients With Elevated PSA After Initial Treatment
Trial ID or NCT#
NCT02673151
Status
NOT RECRUITING
Purpose
The purpose of this research study is to see if recurrent prostate cancer can be identified using a special procedure called a positron emission tomography (PET) scan. PET/CT is used to describe information regarding the function, as well as location and size of a tumor.
Official Title
68-Ga PSMA 11 PET/CT for Detection of Recurrent Prostate Cancer After Initial Therapy in Patients With Elevated PSA
Eligibility Criteria
Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: MALE
Accepts Healthy Volunteers: No
Inclusion Criteria:
- * Histopathological proven prostate adenocarcinoma* Rising prostate-specific antigen (PSA) after definitive therapy with prostatectomy or radiation therapy (external beam or brachytherapy)
- * Post radical prostatectomy (RP) - American Urology Association (AUA) recommendation
- * PSA greater than 0.2 ng/mL measured 6 to 13 weeks after RP * Confirmatory persistent PSA greater than 0.2 ng/mL (total of two PSA measurements greater than 0.2 ng/mL) * Post-radiation therapy -American Society for Radiation Oncology (ASTRO)-Phoenix consensus definition
- * A rise of PSA measurement of 2 or more ng/mL over the nadir* Karnofsky performance status of ≥ 50 (or Eastern Cooperative Oncology Group \[ECOG\] / World Health Organization \[WHO\] equivalent)* Able to provide written consent
Exclusion Criteria:
- * Investigational therapy for prostate cancer.* Unable to lie flat, still or tolerate a positron emission tomograpy (PET) scan.* Prior history of any other malignancy within the last 2 years, other than skin basal cell or cutaneous superficial squamous cell carcinoma that has not metastasized and superficial bladder cancer.
Investigator(s)
Contact us to find out if this trial is right for you.
Contact
David Marcellus
650-723-4547
View on ClinicalTrials.gov
