A Pilot Trial of Adalimumab for the Treatment of Osteoarthritis

Trial ID or NCT#

NCT00185562

Status

not recruiting iconNOT RECRUITING

Purpose

A 12 week trial of Adalimumab in subjects with active erosive inflammatory OA who have ahd an inadequate response to NSAID therapy

Official Title

A Pilot Trial of Adalimumab for the Treatment of Osteoarthritis

Eligibility Criteria

Ages Eligible for Study: Older than 45 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - Age 45 or older, >/=2 tender and 2 swollen joints, inadequate response to NSAID therapy, hand radiographs with evidence of erosive changes, acceptable form of birth control
Exclusion Criteria:
  1. - Autoimmune arthropathy, History of psoriasis, Previous TNF therapy, current use of any DMARD, evidence of TB, history of Hep C, B, or HIV

Investigator(s)

Mark Genovese
Mark Genovese
Rheumatologist
James W. Raitt M.D. Professor, Emeritus