Trial ID or NCT#
The purpose of this study is to test the safety and efficacy of RO6958688 in combination with atezolizumab in treating patients with advanced solid tumors. In Part I (Dose escalation/schedule finding), the study will test increasing doses of RO6958688 administered either weekly or once every three weeks with a fixed dose of atezolizumab administered once every three weeks. In Part II (Dose expansion), the study will look at safety and efficacy of RO6958688 in combination with atezolizumab at the determined dose and schedule in subjects with different levels of CEA-expression in their solid tumors.
An Open-Label, Multicenter, Dose Escalation and Expansion Phase Ib Study to Evaluate the Safety, Pharmacokinetics, and Therapeutic Activity of RO6958688 in Combination With Atezolizumab in Patients With Locally Advanced and/or Metastatic CEA-Positive Solid Tumors
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