Trial ID or NCT#

NCT03114657

Status

RECRUITING

Purpose

This randomized, double-blind, placebo-controlled, parallel-group study will evaluate the efficacy and safety of crenezumab versus placebo in participants with prodromal to mild AD. Participants will be randomized 1:1 to receive either intravenous (IV) infusion of crenezumab or placebo every 4 weeks (q4w) for 100 weeks. The primary efficacy assessment will be performed at 105 weeks. The participants who do not enter open-label extension will enter for a long term follow-up period for up to 52 weeks after the last crenezumab dose (Week 153).

Official Title

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study of Crenezumab in Patients With Prodromal to Mild Alzheimer's Disease

Eligibility Criteria

Ages Eligible for Study: 50 Years to 85 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No

Investigator(s)

Sharon Sha, MD, MS
Memory disorders specialist, Movement disorders specialist
Clinical Associate Professor, Neurology & Neurological Sciences

Contact us to find out if this trial is right for you.

CONTACT

Jennifer Gaudioso
(650) 724-4131