Biomarkers

Trial ID or NCT#

NCT02375165

Status

not recruiting iconNOT RECRUITING

Purpose

Acquired lymphedema is a disease that causes chronic swelling of the limb(s). It is frequently under-recognized or misdiagnosed. This study is designed to lead to the development of an accurate, noninvasive, blood test to allow testing for lymphedema. This approach is particularly useful to investigate relative responses to treatment interventions.

Official Title

Biomarkers for the Detection of Lymphatic Insufficiency

Eligibility Criteria

Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
  1. For lymphedema participants:
    1. * clinical diagnosis of lymphedema of at least 6 months' duration
  2. Control participants:
    1. * no evidence of lymphedema
  3. Exclusion Criteria
  4. For lymphedema participants:
    1. * active cancer* infection* bleeding tendency* active coronary artery disease* congestive heart failure* history of stroke or transient ischemic attack (TIA)* uncontrolled hypertension* renal insufficiency (serum creatinine \> 1.1)* active inflammatory or autoimmune disease (other than lymphedema)
  5. For control participants:
    1. * lymph node dissection* radiation therapy* active inflammatory disease
Exclusion Criteria:
  1. For lymphedema participants:
    1. * active cancer* infection* bleeding tendency* active coronary artery disease* congestive heart failure* history of stroke or transient ischemic attack (TIA)* uncontrolled hypertension* renal insufficiency (serum creatinine \> 1.1)* active inflammatory or autoimmune disease (other than lymphedema)
  2. For control participants:
    1. * lymph node dissection* radiation therapy* active inflammatory disease
View All Criteria
Show Less

Investigator(s)

Stanley G. Rockson, MD
Stanley G. Rockson, MD
Cardiologist
Allan and Tina Neill Professor of Lymphatic Research and Medicine

View on ClinicalTrials.gov