Bone Marrow Sparing Image-Guided Radiation Therapy (RT) Incorporating Novel Use of GCSF and FDG-PET Imaging
Trial ID or NCT#
NCT04514692
Status
RECRUITING
Purpose
This is a research study using Granulocyte Colony Stimulating Factor (GCSF) as a bone marrow stimulating agent for imaging to guide radiation treatment planning. G-CSF is a type of growth factor. Growth factors are proteins made in the body. G-CSF is a type of growth factor that makes the bone marrow produce white blood cells to reduce the risk of infection after some types of cancer treatment.
Official Title
Phase 1 2 Study of Individualized Bone Marrow Sparing Image Guided Radiotherapy Incorporating Novel Use of Granulocyte Colony Stimulating Factor and FDG PET Imaging
Eligibility Criteria
Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: Female
Accepts Healthy Volunteers: No
Inclusion Criteria:
- - 2018 international Federation of Gynecology and Obstetrics (FIGO) stage I IIIC1 cervix cancer with no prior treatment or stage IIIA IIIC1 endometrial cancer status post hysterectomy and lymph node assessment - No required para aortic or extended field radiation - Eastern Cooperative Oncology Group (ECOG) performance status 0 2 - Adequate kidney function (serum Cr <1.5 or creatinine clearance >50 mg/dl) - Adequate bone marrow function (white blood cells > 3.0 X 109/L, platelets >100 x 109/L) - Ability to understand and the willingness to sign a written informed consent document.
Exclusion Criteria:
- - Treatment for other cancer in the past 2 years - Previous pelvic radiation - Medical condition that prevents receiving chemotherapy
Investigator(s)
Contact us to find out if this trial is right for you.
Contact
Neha Aidasani
650-721-4076
View on ClinicalTrials.gov
