Bone Marrow Sparing Image-Guided Radiation Therapy (RT) Incorporating Novel Use of GCSF and FDG-PET Imaging

Trial ID or NCT#



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This is a research study using Granulocyte Colony Stimulating Factor (GCSF) as a bone marrow stimulating agent for imaging to guide radiation treatment planning. G-CSF is a type of growth factor. Growth factors are proteins made in the body. G-CSF is a type of growth factor that makes the bone marrow produce white blood cells to reduce the risk of infection after some types of cancer treatment.

Official Title

Phase 1 2 Study of Individualized Bone Marrow Sparing Image Guided Radiotherapy Incorporating Novel Use of Granulocyte Colony Stimulating Factor and FDG PET Imaging

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: Female
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - 2018 international Federation of Gynecology and Obstetrics (FIGO) stage I IIIC1 cervix cancer with no prior treatment or stage IIIA IIIC1 endometrial cancer status post hysterectomy and lymph node assessment - No required para aortic or extended field radiation - Eastern Cooperative Oncology Group (ECOG) performance status 0 2 - Adequate kidney function (serum Cr <1.5 or creatinine clearance >50 mg/dl) - Adequate bone marrow function (white blood cells > 3.0 X 109/L, platelets >100 x 109/L) - Ability to understand and the willingness to sign a written informed consent document.
Exclusion Criteria:
  1. - Treatment for other cancer in the past 2 years - Previous pelvic radiation - Medical condition that prevents receiving chemotherapy


Elizabeth Kidd
Elizabeth Kidd
Radiation oncologist
Associate Professor of Radiation Oncology (Radiation Therapy)

Contact us to find out if this trial is right for you.


Neha Aidasani