Trial ID or NCT#





RATIONALE: Drugs used in chemotherapy work in different ways to stop tumor cells from dividing so they stop growing or die. Radiation therapy uses high-energy x-rays to damage tumor cells. Giving more than one chemotherapy drug with radiation therapy may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving intrathecal and systemic combination chemotherapy together with radiation therapy works in treating young patients with newly diagnosed central nervous system (CNS) atypical teratoid/rhabdoid tumors.

Official Title

A Phase II Study of Intrathecal and Systemic Chemotherapy With Radiation Therapy for Children With Central Nervous System Atypical Teratoid/Rhabdoid Tumor (AT/RT) Tumor

Eligibility Criteria

Ages Eligible for Study: Younger than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No


Paul Graham Fisher, MD
Neuro-oncologist, Pediatric neurologist
Bing Director of the Program in Human Biology, Beirne Family Professor of Pediatric Neuro-Oncology, Professor of Pediatrics and, by courtesy, of Neurosurgery at SUMC

Contact us to find out if this trial is right for you.


Paul Fisher
(650) 725-8630