Controlled Ventilation CT in CF Infants
Trial ID or NCT#
NCT01200888
Status
NOT RECRUITING
Purpose
The objective of the study is to implement a new method of performing chest CT imaging in young children with cystic fibrosis at Packard Children's Hospital. This technique will be used to evaluate early lung disease comparing quantitative chest CT air trapping and airway measurements with lung function measurements in infants, toddlers, and young children with chronic lung disease.
Official Title
Differentiating Outcome Measures in Infants/Young Children With Cystic Fibrosis Utilizing Controlled Ventilation Infant/Young Child Chest CT Scanning and Lung Function Testing
Eligibility Criteria
Ages Eligible for Study: 2 Months to 5 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
- 1. Infants and young children (age ~ 2/3 months to < 5 years) 2. Diagnosed with cystic fibrosis with either 2 identified CFTR gene mutations, or a positive sweat chloride 3. Informed consent by parent or legal guardian. 4. Ability to comply with study visit procedures as judged by the investigator.
Exclusion Criteria:
- 1. Acute wheezing and/or respiratory distress at either study visit. 2. Acute intercurrent respiratory infection, defined as an increase in cough, wheezing, or respiratory rate with onset in 1 week preceding Study visit. 3. Oxygen saturation < 90% on room air at study visit. 4. Any medical condition that in the opinion of the investigator precludes subject participation.
Investigator(s)
Terry Robinson
Beverley Newman
Professor of Radiology (Pediatric Radiology)
Contact us to find out if this trial is right for you.
Contact
Colleen Dunn
650-736-0388
View on ClinicalTrials.gov
