Trial ID or NCT#



recruiting iconRECRUITING


Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asymptomatic high-grade carotid stenosis. One trial will randomize patients in a 1:1 ratio to endarterectomy versus no endarterectomy and another will randomize patients in a 1:1 ratio to carotid stenting with embolic protection versus no stenting. Medical management will be uniform for all randomized treatment groups and will be centrally directed.

Official Title

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

Eligibility Criteria

Ages Eligible for Study: Older than 35 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No


Gary K. Steinberg, MD, PhD
Gary K. Steinberg, MD, PhD
Cerebrovascular neurosurgeon, Moyamoya surgeon, Aneurysm neurosurgeon, Neurosurgeon, Neurosurgeon
Bernard and Ronni Lacroute-William Randolph Hearst Professor in Neurosurgery and Neurosciences and Professor, by courtesy, of Neurology
Oliver O. Aalami, MD
Shipra Arya
Shipra Arya
Associate Professor of Surgery (Vascular Surgery) at the Stanford University Medical Center

Contact us to find out if this trial is right for you.


Brittanie D Baughman
650-493-5000 Ext. 68632