Comprehensive Computed Tomography Guidance of Coronary Bypass Graft Surgery
Trial ID or NCT#
NCT03894423
Status
RECRUITING
Purpose
Apply CT angiography, CT perfusion imaging and advanced image processing techniques to improve revascularization decision-making and surgical strategies in patients undergoing coronary artery bypass graft surgery.
Official Title
Comprehensive CT Guided Coronary Bypass Graft Surgery
Eligibility Criteria
Ages Eligible for Study: Older than 40 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
- - Planned elective CABG for coronary artery disease. - CABG is the primary indication for surgery (but may include treatment of mild-moderate valvular disease). - Age: ≥40 years.
Exclusion Criteria:
- - Technical feasibility of the cardiac CT exams: redo-CABG, significant arrhythmia/mal-conduction, congenital conditions, severe valvular disease or cardiomyopathy (to the extent that the CT acquisition is technically challenged), inadequate understanding of the English language (to provide consent or follow instructions during the exams). - Overall safety: unstable clinical condition (clinical heart failure, unstable angina, myocardial infarction <1 month prior). - Radiation risk: pregnancy (cannot be ruled out), body weight >100kg. - CT contrast medium-related: known allergy, renal failure - Vasodilator related: known allergy, bronchial asthma requiring daily use of bronchodilators, Mobitz II or 3rd degree AV block, sick sinus node disease, clinically significant carotid artery narrowing, severe aortic stenosis or LVOT narrowing, systolic blood pressure below 90mmHg, (continued) use of dipyridamole or aminophylline. - Inability to provide informed consent.
Investigator(s)
Koen Nieman
Cardiologist
Professor of Medicine (Cardiovascular Medicine) and of Radiology (CV Imaging)
Contact us to find out if this trial is right for you.
Contact
Sarah Magee
650-723-2300
View on ClinicalTrials.gov
