Cycled Phototherapy

Trial ID or NCT#



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Cycled phototherapy (PT) is likely to increase survival over that with continuous PT among extremely premature infants (< 750 g BW or <27 weeks GA).

Official Title

Cycled Phototherapy: A Safer Effective Method to Control the Serum Bilirubin Of Extremely Premature Infants?

Eligibility Criteria

Ages Eligible for Study: 22 Weeks to 27 Weeks
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. 1. Infants is inborn 2. Infant is ≤ 750 grams at birth and/or < 27 weeks gestation at birth by best OB estimate 3. Infant is 12-36 hours of age.
Exclusion Criteria:
  1. 1. Unable to enroll infant by 36 hours of age 2. Previous phototherapy 3. Known hemolytic disease 4. TSB reported as >6.0 mg/dL before 12 hours age 5. Major anomaly 6. Overt nonbacterial infection 7. Infant is likely to expire soon: Limiting or withdrawal of intensive care is being recommended to the parents, the parents are requesting withdrawal of care, or the pH is < 6.80 or persistent bradycardia with hypoxemia for >2h.


Krisa Van Meurs

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M. Bethany Ball