Trial ID or NCT#

NCT02140983

Status

not recruiting iconNOT RECRUITING

Purpose

The purpose of this study is to evaluate the effects of liraglutide on the memory and attention of people with insulin resistance. Liraglutide is a medication that makes the body more sensitive to insulin, and therefore may allow it to manage sugar more effectively. The investigators are looking specifically at a region of the brain that is associated with memory and attention, called the hippocampus, in order to see whether treatment this treatment will change performance on memory and attention tasks. The investigators are also taking an MRI of the brain to see whether there are changes to the size and shape of the hippocampus after treatment. All subjects in this study will be 50-70 years old and have pre- diabetes. Half of all subjects will have a family history of dementia, while the other half will not.

Official Title

Effects of Liraglutide on Hippocampal Structure and Function in Aging Adults With Prediabetes

Eligibility Criteria

Ages Eligible for Study: 50 Years to 70 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes

Investigator(s)

Natalie L. Rasgon
Natalie L. Rasgon
Psychiatrist
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult) at the Stanford University Medical Center, Emerita

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CONTACT

Kathleen Watson
(646) 245-8434