Feasibility 3D Perfusion Ultrasound for Liver Cancer SABR Planning and Response Evaluation

Trial ID or NCT#



not recruiting iconNOT RECRUITING


The purpose of this study is to prospectively analyze the value of 3D ultrasound perfusion imaging for treatment planning, the prediction of therapy success, and to monitor the treatment response in patients with a primary or metastatic liver tumor undergoing radiation treatment.

Official Title

Feasibility of 3D Perfusion Ultrasound for Liver Cancer SABR Planning and Response Evaluation

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. * Ability to understand and willingness to sign the written informed consent document* Patient with primary liver tumor or metastasis scheduled for Stereotactic Ablative Radiotherapy (SABR)* Patient is at least 18 years of age. No gender/race-ethnic restrictions.* Performance status (ECOG) between 0-3* History and Physical done within 4 weeks of enrollment.
Exclusion Criteria:
  1. * Patient has previously been enrolled in and completed this study.* Known right to left cardiac shunt, bidirectional or transient.* Patient has any medical condition or other circumstances which would significantly decrease the chances of obtaining reliable data, achieving study objectives, or completing the study and/or post-dose follow-up examinations.* History of hypersensitivity to the contrast agent perflutren* History of pulmonary hypertension* Patients who are pregnant or are trying to become pregnant


Aya Kamaya, MD
Aya Kamaya, MD
Professor of Radiology (Body Imaging)
Dimitre Hristov

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Jen-Yeu Wang