F18 DCFPyL PET/CT in Imaging Participants With Recurrent Prostate Cancer

Trial ID or NCT#

NCT03501940

Status

not recruiting iconNOT RECRUITING

Purpose

This study provides fluorine F 18 DCFPyL positron emission tomography/computed tomography (PET/CT) to participants with prostate cancer that has come back. Diagnostic procedures, such as fluorine F 18 DCFPyL PET/CT, may help find and diagnose prostate cancer and find out how far the disease has spread.

Official Title

18F-DCFPyL PET/CT in the Evaluation of Patients With Biochemical Recurrence of Prostate Cancer and Non-Contributory CT Scans

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. * Biopsy proven prostate adenocarcinoma* Rising PSA after definitive therapy with prostatectomy or radiation therapy (external beam or brachytherapy)
  2. * Post radical prostatectomy (RP) - American Urological Association (AUA) recommendation
  3. * PSA greater than 0.2 ng/mL measured after at least 6 weeks from radical prostatectomy * Confirmatory persistent PSA greater than 0.2 ng/mL (total of two PSA measurements greater than 0.2 ng/mL) * Post-radiation therapy - American Society for Radiation Oncology (ASTRO) - Phoenix consensus definition
  4. * A rise of PSA measurement of 2 or more ng/mL over the nadir* Able to provide written consent* Karnofsky performance status of \> 50 (or Eastern Cooperative Oncology Group \[ECOG\] / World Health Organization \[WHO\] equivalent)
Exclusion Criteria:
  1. * Unable to provide informed consent* Inability to lie still for the entire imaging time* Inability to complete the needed investigational and standard-of-care imaging examinations due to other reasons (severe claustrophobia, radiation phobia, etc.)* Any additional medical condition, serious intercurrent illness, or other extenuating circumstance that, in the opinion of the Investigator, may significantly interfere with study compliance
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Investigator(s)

Andrei Iagaru
Andrei Iagaru
Radiologist
Professor of Radiology (Nuclear Medicine)

Contact us to find out if this trial is right for you.

Contact

Pranav Hegde
650-721-4080

View on ClinicalTrials.gov