Trial ID or NCT#





The purpose of this study is to determine whether shotgun sequencing technology, which can be used to detect donor DNA in recipient plasma, can be used as a rapid, accurate, non-invasive method to detect Acute Cellular Rejection (ACR) after heart transplantation. Currently, all heart transplant recipients undergo invasive heart biopsies to diagnose ACR. Thus, there is an ongoing need to monitor patients for the development of acute and chronic rejection, with the primary goal of non-invasive early detection and treatment to prevent organ damage.

Official Title

Genome Transplant Dynamics: Non-Invasive Sequencing-Based Diagnosis of Rejection

Eligibility Criteria

Sexes Eligible for Study: All
Accepts Healthy Volunteers: No


Kiran Kaur Khush, MD, MAS
Cardiologist, Heart failure cardiologist
Associate Professor of Medicine (Cardiovascular Medicine) at the Stanford University Medical Center

Contact us to find out if this trial is right for you.


Spectrum Child Health
(650) 724-1175