Trial ID or NCT#



not recruiting iconNOT RECRUITING


We hope to learn how a brain circuit that is important to the understanding of depression, anhedonia and positive affect responds to a novel pharmaceutical treatment for depression and related symptoms. Adults who have a diagnosis of major depression and are not completely responsive to antidepressant medication will be sought out for participation; as will an equal number of adults not suffering from the disorder. Those suffering from depression will be given pramipexole, an investigational medication for eight weeks during which information will be collected about mood, cognition, and brain function. Adults not suffering from depression will also be evaluated with these measures.

Official Title

Imaging the Nucleus Accumbens in Major Depressed Patients 'Treated With Pramipexole

Eligibility Criteria

Ages Eligible for Study: 20 Years to 65 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes


Jennifer Keller
Jennifer Keller
Clinical Associate Professor, Psychiatry and Behavioral Sciences Clinical Associate Professor, Psychiatry and Behavioral Sciences
Vinod Menon

Contact us to find out if this trial is right for you.


Jennifer Keller, PHD
(650) 724-0070