Integrated Whole-Genome Analysis of Hematologic Disorders

Trial ID or NCT#

NCT01108159

Status

not recruiting iconNOT RECRUITING

Purpose

We will use new technologies to look at the DNA, RNA, proteins, and metabolites in the disease-containing blood, bone marrow, or tissue and normal cells from the skin. Our goal is to analyze all of the genes in the diseased and normal skin sample. By comparing the results of the diseased sample and normal skin cells and the results of the two types of genetic information (DNA and RNA), we should be able to identify genetic changes that are important for the initiation, progression, or treatment response of that particular disorder.

Official Title

Integrated Whole-Genome Analysis of Hematologic Disorders Using High-Throughput Sequencing and Array Technologies

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. 1. 18 years of age or older 2. Patient meets the clinical and/or pathologic criteria for the hematologic disorder being examined. 3. Patient is willing to provide a skin biopsy and five 10 mL tubes of peripheral blood.
Exclusion Criteria:
  1. 1. Less than 18 years of age 2. Patient is not willing to provide a skin biopsy and five 10 mL tubes of peripheral blood.

Investigator(s)

James L. Zehnder, M.D.
James L. Zehnder, M.D.
Hematologist, Pathologist
Professor of Pathology (Research) and of Medicine (Hematology)
Scott D. Boyd, MD PhD
Scott D. Boyd, MD PhD
Pathologist, Hematopathologist
Stanford Professor of Food Allergy and Immunology and Professor of Pathology
Jason Gotlib
Hematologist-Oncologist
Professor of Medicine (Hematology)

Contact us to find out if this trial is right for you.

Contact

Jason D Merker
650-922-1885