Increasing the Removal of Protein-Bound Solutes During Extended Hours Hemodialysis

Trial ID or NCT#

NCT01892839

Status

recruiting iconRECRUITING

Purpose

Hemodialysis keeps patients with renal failure alive but does not restore normal health. Retention of chemicals that bind to plasma proteins and are therefore poorly removed by dialysis may contribute to ill health in patients receiving conventional treatment. This proposal will test the effect of a new method designed to improve the removal of protein-bound solutes during dialysis. The effects on blood chemical levels of two different dialysis prescriptions will be tested in patients already undergoing nocturnal in-center hemodialysis three times weekly.

Official Title

Increasing the Removal of Protein-Bound Solutes During Extended Hours Hemodialysis

Eligibility Criteria

Ages Eligible for Study: 18 Years to 85 Years
Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. * stable on nocturnal in-center dialysis located close to Stanford University and VA Palo Alto
Exclusion Criteria:
  1. * recent use of antibiotics* gastrointestinal disease

Investigator(s)

Timothy Meyer

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Contact

Timothy Meyer, MD
650-852-3314