Imaging Kidney Transplant Rejection Using Ferumoxytol-Enhanced Magnetic Resonance

Trial ID or NCT#



not recruiting iconNOT RECRUITING


The goal of this study is to develop a non-invasive imaging test for in vivo detection of kidney transplant rejection. The hypotheses are that 1) Ferumoxytol-MRI can generate accurate estimates of tissue iron concentrations and tissue macrophages. 2) The signal given by a renal allograft on Ferumoxytol-MRI demonstrates significant differences between rejected and non-rejected transplants.

Official Title

Non-invasive MR Imaging Diagnosis of Transplant Rejection

Eligibility Criteria

Ages Eligible for Study: 8 Years to 40 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
  1. - Completed solid organ transplant with referral for transplant follow-up
Exclusion Criteria:
  1. - Exclusion criteria comprise MR-incompatible metal implants, need of sedation (since an anesthesia is not supported by this), claustrophobia or hemosiderosis/hemochromatosis.


Heike Daldrup-Link
Heike Daldrup-Link
Pediatric radiologist
Professor of Radiology (General Radiology) and, by courtesy, of Pediatrics (Hematology/Oncology)

Contact us to find out if this trial is right for you.


Anne Sawyer