Immune Tolerance Dysfunction in Pregnancy Due to Ambient Air Pollution Exposure

Trial ID or NCT#

NCT04549142

Status

not recruiting iconNOT RECRUITING

Purpose

The purpose of this project is to study the effects of air pollution toxicants on pregnant mothers' immune health during and after pregnancy. Using already collected samples, this study proposes to evaluate changes in immune function in response to air pollution with the use of innovative technologies, to identify the drivers of immune dysfunction and potential modifiable factors, and to determine how these immune findings are associated with pollution exposure and outcomes of disease.

Official Title

Immune Tolerance Dysfunction in Pregnancy Due to Ambient Air Pollution

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: FEMALE
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
  1. * Pregnant women: at 18-25 weeks gestation at time of eligibility screening and baseline visit
Exclusion Criteria:
  1. * Having smoked more than 50 cigarettes during pregnancy* A history of autoimmune diseases, HIV or cancer
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Investigator(s)

R. Sharon Chinthrajah
R. Sharon Chinthrajah
Allergist, Immunologist, Pulmonologist
Associate Professor of Medicine (Sean Parker Center) and of Pediatrics (Allergy and Clinical Immunology)

View on ClinicalTrials.gov