Trial ID or NCT#

NCT02090140

Status

recruiting iconRECRUITING

Purpose

The purpose of this study is to compare two biologic methods for the treatment of articular cartilage defects in the knee. The first method, microfracture, is the standard of care and is routinely used to recruit cells from the subchondral bone marrow to the site of cartilage loss. The second method is the application of adipose-derived stem cells (ADSCs) to the defect site. In theory, ADSCs on a collagen scaffold should enable the delivery of more specific progenitor cells to the site of injury, resulting in better regeneration and integration of articular cartilage at the site of a defect as compared to the microfracture method.

Official Title

Randomized Controlled Trial of Microfracture Versus Adipose Derived Stem Cells for the Treatment of Isolated Articular Cartilage Defects

Eligibility Criteria

Ages Eligible for Study: 18 Years to 50 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No

Investigator(s)

Seth Lawrence Sherman, MD
Seth Lawrence Sherman, MD
Sports medicine surgeon, Shoulder surgeon, Orthopaedic surgeon
Associate Professor of Orthopaedic Surgery

Contact us to find out if this trial is right for you.

CONTACT

Jan Yabut
(650) 721-7780