Trial ID or NCT#

NCT01559857

Status

NOT RECRUITING

Purpose

The purpose of this study is to see how an insulin sensitizing medication, Pioglitazone, can cause changes in mood in some depressed patients. Study participants receive assessment of their cognitive and metabolic functioning. If they meet criteria, they will be asked to take either Pioglitazone or a placebo for a 90-day trial. Participants will undergo an Oral Glucose Tolerance Test to measure fasting insulin and glucose levels, as well as routine blood testing. The investigators hope to quantify the role of Pioglitazone in patients with mood disorders and compare the values to those previously obtained in a healthy age-matched control population. The investigators also hope to examine the association between IR and cognitive performance and clinical course of depression in patients with mood disorders.

Official Title

Pioglitazone Treatment for Insulin Resistant Patients With Mood Disorders

Eligibility Criteria

Ages Eligible for Study: 20 Years to 65 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No

Investigator(s)

Natalie L. Rasgon
Psychiatrist
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology-Adult) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine) at the Stanford University Medical Center

Contact us to find out if this trial is right for you.

CONTACT

Rachael Lazar
(650) 724-4559