Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients

Trial ID or NCT#

NCT01419275

Status

not recruiting iconNOT RECRUITING

Purpose

Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya disease and stroke patients

Official Title

Quantifying Collateral Perfusion in Cerebrovascular Disease-Moyamoya Disease and Stroke Patients

Eligibility Criteria

Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
  1. Moyamoya Patient Inclusion Criteria: - Men and non-pregnant women, at least 21 years of age. - Outpatients seen at the Stanford Neurosurgery and Neurology Departments. - Ability to comply with all studies. - Inclusion of Moyamoya patients with Sulfa allergies. - Patients diagnosed with or suspected to have Moyamoya disease. Stroke Patient Inclusion Criteria: - Men and non-pregnant women, at least 21 years of age. - Patients admitted to the inpatient Stanford Stroke Service for stroke-like symptoms, less than 24 hours from last time seen normal. - Ability to comply with all studies. Clinical Patient Acetazolamide MRI Inclusion Criteria: - Men and non-pregnant women, at least 21 years of age. - Patients admitted to the inpatient Stanford Stroke Service or Neurosurgical -Service for symptoms compatible with cerebrovascular disease. - Ability to comply with all studies. Normal Subject Inclusion Criteria: - Ability to comply with the MRI study.
Exclusion Criteria:
  1. - Level of consciousness score of 2 or greater as defined by the NIH stroke scale. - Symptoms likely related to psychoactive drugs or patients with symptoms related to an active inflammatory disease such as AIDS, meningitis, or cerebritis. - Psychiatric or substance abuse disorder or dementia that interferes with evaluation or interpretation of the neurologic and mental assessment of these patients. - Informed consent cannot be obtained either from the patient or legal representative. - Severe coexisting or terminal systemic disease that limits life expectancy or that may interfere with the conduct of the study. - Symptoms related to an alternative diagnosis such as seizures or migraine. - Patients receiving any thrombolytic agent or receiving acute stroke investigational drug therapies during the 30-day study.
View All Criteria
Show Less

Investigator(s)

Greg Zaharchuk
Radiologist, Neuroradiologist
Professor of Radiology (Neuroimaging and Neurointervention)
Huy M. Do, MD
Huy M. Do, MD
Interventional neuroradiologist, Radiologist
Professor of Radiology (Neuroimaging and Neurointervention) and, by courtesy, of Neurosurgery and of Otolaryngology - Head & Neck Surgery (OHNS)

Contact us to find out if this trial is right for you.

Contact

Sandra Dunn
650-724-8278

View on ClinicalTrials.gov