Study of Cobimetinib in Participants With Solid Tumors

Trial ID or NCT#

NCT00467779

Status

not recruiting iconNOT RECRUITING

Purpose

This non-randomized, open-label, study will determine the highest safe dose of cobimetinib, how often it should be taken, how well participants with cancer tolerate cobimetinib and will assess the pharmacokinetic effect of midazolam and dextromethorphan on the study drug.

Official Title

A Phase 1 Dose-Escalation Study of the Safety and Pharmacokinetics of GDC-0973/XL518 Administered Orally Daily to Subjects With Solid Tumors

Eligibility Criteria

Sexes Eligible for Study: ALL
Accepts Healthy Volunteers: No

Investigator(s)

Branimir I Sikic

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Contact

Cancer Clinical Trials Office
650-498-7061