Study of Dextromethorphan in OCD and Related Disorders
Trial ID or NCT#
NCT04899687
Status
RECRUITING
Purpose
The purpose of the study is to assess the tolerability and efficacy of dextromethorphan in combination with fluoxetine for symptom relief in OCD and related disorders.
Official Title
Fluoxetine/Dextromethorphan in Obsessive-Compulsive and Related Disorders: an Open-Label Crossover Pilot Study
Eligibility Criteria
Ages Eligible for Study: 18 Years to 65 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
- - Diagnosis of obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), illness anxiety disorder (IAD) or somatic symptom disorder (SSD) - Living within California - Capacity to provide informed consent
Exclusion Criteria:
- - Current bipolar disorder or psychotic disorder - Active moderate or severe substance use disorder, lifetime severe substance use disorder - Pregnant or nursing women - Use of prescribed psychotropic medications other than fluoxetine for 2 weeks prior to study start - Having commenced OCD-targeted exposure and response-prevention (ExRP) psychotherapy within 2 months of study start
Investigator(s)
Peter Johannes van Roessel
Clinical Associate Professor, Psychiatry and Behavioral Sciences
Carolyn Rodriguez
Psychiatrist
Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
Contact us to find out if this trial is right for you.
Contact
Pavithra Makunda, MS
650-723-4095
View on ClinicalTrials.gov
