Treatment Trial for Psychogenic Nonepileptic Seizures

Trial ID or NCT#

NCT00835627

Status

recruiting iconRECRUITING

Purpose

The investigators propose that patients who receive targeted pharmacotherapy (sertraline) or focused psychotherapy (cognitive behavioral therapy-informed psychotherapy (CBT-ip) for NES) or combined treatment (CBT-ip + sertraline) will report fewer nonepileptic seizures (NES) compared to patients who receive community care / treatment as usual (TAU). The purpose of this study is to provide pilot testing and data to inform the future multicenter randomized controlled trial based on the hypothesis.

Official Title

Medication and Psychotherapy Treatment Trial for Psychogenic Nonepileptic Seizures

Eligibility Criteria

Ages Eligible for Study: 18 Years to 95 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. - Video electroencephalogram (EEG) confirmed diagnosis of NES - Have at least one nonepileptic seizure per month - Able to complete self report symptom scales - Not receiving optimized sertraline
Exclusion Criteria:
  1. - Equivocal EEG findings - using monoamine oxidase inhibitors (MAOIs), pimozide, or sumatriptan - allergy/sensitivity to sertraline - current alcohol/drug dependence - serious medical illness requiring current hospitalization
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Investigator(s)

Charles DeBattista
Charles DeBattista
Psychiatrist
Professor of Psychiatry and Behavioral Sciences (General Psychiatry and Psychology - Adult)

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Contact

Jessica Hawkins
6507238323

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View on ClinicalTrials.gov