The "Prediction of Alcohol Withdrawal Severity Scale" (PAWSS)

Trial ID or NCT#



not recruiting iconNOT RECRUITING


Although there are several tools that can be used to evaluate the severity of ongoing alcohol withdrawal syndrome (AWS), there is no available tool that can predict which patients are at risk for developing AWS at the time admission, before the patient has developed AWS. Unfortunately, there are severe symptoms of alcohol withdrawal (e.g., seizures) which may develop early in the hospitalization, and before the development of other systemic symptoms which may warn medical personnel of the possibility of impeding alcohol withdrawal (e.g., autonomic instability, delirium). The goal of this study is to evaluate the psychometric properties (e.g., predictive validity) of a new tool, the Prediction of Alcohol Withdrawal Severity Scale (PAWSS), on identifying which patients are at risk for developing complicated AWS (i.e., seizures, hallucinosis, delirium tremens) among hospitalized, medically ill patients.

Official Title

The "Prediction of Alcohol Withdrawal Severity Scale" (PAWSS): Development and Psychometric Characteristics of a New Scale for the Prediction of Complicated Alcohol Withdrawal Syndrome.

Eligibility Criteria

Ages Eligible for Study: Older than 18 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: Yes
Inclusion Criteria:
  1. - Adult patients - defined as 18+ years of age - Able to understand and communicate in English. - Admission to the hospital within the last 24 hours to selected Stanford Hospital and Clinics inpatient units from the ED, outpatient clinics/community, or other SHC medical units. - Without an imminent discharge plan, (within 48 hours of study screening). - Willing and able to freely consent and participate.
Exclusion Criteria:
  1. - Unable or unwilling to consent and participate. - Unable to understand and communicate in English. - Patients transferred from outside medical facilities. - Patients with imminent discharge plan (i.e., not expected to remain in the hospital for at least 48 hours after enrollment into the study) - Uncontrolled active seizure disorder. - Active severe AWS (as defined by CIWA = or > 20) on initial assessment. - Identified by the primary team as too sick to participate.


Jose R. Maldonado, MD, FACLP, FACFE
Jose R. Maldonado, MD, FACLP, FACFE
Psychiatrist, Transplant psychiatrist, Neuropsychiatrist
John and Terry Levin Family Professor of Medicine and Professor, by courtesy, of Emergency Medicine and of Medicine