Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD
Trial ID or NCT#
NCT04532424
Status
NOT RECRUITING
Purpose
Investigating the efficacy of a form of TMS called theta-burst stimulation for restricted and repetitive behavior in ASD.
Official Title
Transcranial Magnetic Stimulation for Restricted and Repetitive Behavior in ASD
Eligibility Criteria
Ages Eligible for Study: 12 Years to 45 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
- 1. Diagnosis of Autism Spectrum Disorder (ASD), Asperger's or Autism. 2. Meet criteria for ASD on clinical assessments (ADOS-2 or CARS/BOSA if conducted remotely & ADI-R) 3. Aged between 12-45 years old 4. Have a reliable informant who can complete relevant questionnaires 5. Must have previously not responded or not tolerated 2 treatments.
Exclusion Criteria:
- 1. Any contraindications for TMS e.g. history of seizures 2. Pregnancy 3. Any current or past history of any physical condition which in the investigator's opinion might put the subject at risk or interfere with study results interpretation. 4. Active substance use (<1 week) or intoxication verified by toxicology screen--of cocaine, amphetamines, benzodiazepines 5. Showing symptoms of withdrawal from alcohol or benzodiazepines 6. DSM-5 diagnosis of bipolar disorder or a psychotic disorder e.g. schizophrenia. 7. Significant sensory impairments such as blindness or deafness. 8. Any other indication the PI feels would comprise data 9. Current severe insomnia (must sleep a minimum of 4 hours the night before stimulation) 10. IQ<50 or not testable using IQ measures and no historical IQ score available 11. Currently taking Clozapine or another medication that the PI determines increases the risk of TMS or may disrupt the efficacy. 12. A motor threshold that is too high to allow safe/tolerable treatment.
Investigator(s)
Contact us to find out if this trial is right for you.
Contact
Eleanor J Cole, PhD
View on ClinicalTrials.gov
