The Anchor Study: Digitally Delivered Intervention for Reducing Problematic Substance Use

Trial ID or NCT#



not recruiting iconNOT RECRUITING


This study aims to validate W-SUDs as a digitally-delivered substance use disorder program through a fully-powered randomized control trial that will test the comparative efficacy of the mobile-app based substance use disorder program (W-SUDs) to reduce substance use relative to a psychoeducation control condition, which has no cognitive behavioral therapy and the content is not delivered through a conversational user interface.

Official Title

Woebot for Substance Use Disorders Phase 2 RCT: Digitally Delivered Intervention for Reducing Problematic Substance Use

Eligibility Criteria

Ages Eligible for Study: 18 Years to 65 Years
Sexes Eligible for Study: All
Accepts Healthy Volunteers: No
Inclusion Criteria:
  1. 1. Have a smartphone 2. Endorse a substance use concern 3. Be between 18 and 65 years of age 4. Be available and committed to engage with the Woebot app 5. Be literate in English. (This is required for inclusion because all materials will be in English).
Exclusion Criteria:
  1. 1. Pregnancy (as W-SUDs will not be specifically developed to address the unique needs of this population) 2. Suicide attempt within the past year (12 months) 3. Symptoms of severe drug/alcohol history: History of delirium tremens; Experiencing hypertension, drenching sweats, seizures or confusion after stopping alcohol or drugs; Liver trouble (cirrhosis or hepatitis); Convulsions or GI bleeding due to drug/alcohol use 4. Opioid overdose within the past year (12 months) 5. Opioid misuse without medication-assisted treatment 6. Not residing in the U.S. 7. Previous Woebot use


Judith Prochaska
Senior Associate Vice Provost, Clinical Research Governance and Professor of Medicine (Stanford Prevention Research Center)