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Primary cervical tracheal monophasic synovial sarcoma confirmed by SYT-SSX gene rearrangement JOURNAL OF LARYNGOLOGY AND OTOLOGY Corrales, C. E., Berry, G., Damrose, E. J. 2011; 125 (6): 651-654

Abstract

To review the existing diagnostic modalities and treatment for primary tracheal synovial sarcoma, and to report a case of primary cervical synovial sarcoma arising in the trachea.Retrospective.Head and neck surgery unit at a tertiary university centre.One case of primary cervical tracheal monophasic synovial sarcoma diagnosed by SYT-SSX gene rearrangement.This patient underwent surgical resection of the synovial sarcoma, together with tracheal resection and primary anastomosis assisted by laryngeal-releasing manoeuvres, without complication.Clinical, radiographical, pathological and surgical information were collected.One year post-operatively, there was no evidence of recurrence.Synovial sarcoma arising in the trachea is very rare. Diagnosis is confirmed by demonstrating the SYT-SSX gene rearrangement. The first-line treatment is surgery.

View details for DOI 10.1017/S0022215110002975

View details for Web of Science ID 000292101800023

View details for PubMedID 21281530