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Subcutaneous nodular amyloidosis: A case report and review of the literature HUMAN PATHOLOGY Nguyen, T. U., Oghalai, J. S., McGregor, D. K., Janssen, N. M., Huston, D. P. 2001; 32 (3): 346-348

Abstract

Amyloidosis typically manifests with disseminated infiltration of multiple organ systems. Rarely, amyloidosis may be localized. We report a patient with localized subcutaneous nodular amyloidosis, without systemic amyloid involvement or myeloma, whose presenting symptom was multiple discrete neck nodules. Immunohistochemical analysis showed the amyloid deposits to be derived from lambda light chains. Twenty-four month follow-up showed minimal disease progression. A literature review showed only 5 reported cases of subcutaneous nodular amyloidosis. This is the first description of a patient with subcutaneous nodular amyloidosis derived from lambda light chains. HUM PATHOL 32:346-348.

View details for Web of Science ID 000167821100017

View details for PubMedID 11274647