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Investigation of False-Positive Results Given by the QuantiFERON-TB Gold In-Tube Assay
Investigation of False-Positive Results Given by the QuantiFERON-TB Gold In-Tube Assay JOURNAL OF CLINICAL MICROBIOLOGY Slater, M., Parsonnet, J., Banaei, N. 2012; 50 (9): 3105-3107Abstract
We investigated a sudden increase in the rate of positive QuantiFERON-TB Gold In-Tube results from 10% to 31% at a U.S. academic institution. Direct comparison of the TB antigen tubes with tubes from a different lot number identified that a potential problem with the TB antigen vials in a certain tube lot was the likely cause of the elevated positive rate. The underlying defect remains unknown. This finding warrants refinement of quality control programs by the manufacturer and users.
View details for DOI 10.1128/JCM.00730-12
View details for Web of Science ID 000307941900046
View details for PubMedID 22785197
View details for PubMedCentralID PMC3421800