Notice: Users may be experiencing issues with displaying some pages on stanfordhealthcare.org. We are working closely with our technical teams to resolve the issue as quickly as possible. Thank you for your patience.
 

Learn about the flu shot, COVID-19 vaccine, and our masking policy »

Stanford Health Care

BABOON-TO-HUMAN CARDIAC XENOTRANSPLANTATION IN A NEONATE JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION Bailey, L. L., NEHLSENCANNARELLA, S. L., Concepcion, W., JOLLEY, W. B. 1985; 254 (23): 3321-3329

Abstract

This report details the first case of cardiac xenotransplantation in a neonate. The recipient, a victim of hypoplastic left heart syndrome (HLHS), survived 20 days. Autopsy findings are documented. The cardiac graft showed only traces of cell-mediated rejection. Graft failure appears to have resulted from a progressive, potentially avoidable humoral response, unmodified by immunosuppression. Cardiac allotransplantation and selective baboon-to-human xenotransplantation deserve further exploration as investigational therapy for neonatal HLHS.

View details for Web of Science ID A1985AVW1000017

View details for PubMedID 2933538