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DIABETIC-KETOACIDOSIS - BIOCHEMISTRY, PHYSIOLOGY, TREATMENT, AND PREVENTION PEDIATRIC CLINICS OF NORTH AMERICA Krane, E. J. 1987; 34 (4): 935-960

Abstract

Diabetic ketoacidosis (DKA) is the most common cause of death of juvenile-onset diabetics, and as such represents an important issue for pediatricians. In this article, the author reviews the endocrinology of insulin and the glucose counter-regulatory hormones, which are the basis for the development of DKA. The effects of hyperglycemia and acidosis upon organ physiology are detailed, and this serves as the foundation for subsequent discussion of the management of the patient with DKA. Finally, the author summarizes current strategies for prevention of DKA in patients with diabetes.

View details for Web of Science ID A1987J442600009

View details for PubMedID 3112717