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COMPARISON OF URINARY HUMAN FOLLICLE-STIMULATING-HORMONE AND HUMAN MENOPAUSAL GONADOTROPINS FOR OVARIAN STIMULATION IN AN INVITRO FERTILIZATION PROGRAM FERTILITY AND STERILITY Scoccia, B., Blumenthal, P., Wagner, C., Prins, G., Scommegna, A., Marut, E. L. 1987; 48 (3): 446-449

Abstract

This report compares the effects of human menopausal gonadotropin (hMG) and purified urinary human follicle-stimulating hormone (hFSH) protocols in patients with irreparable tubal disease as the sole indication for in vitro fertilization-embryo transfer (IVF-ET). The hFSH protocol was associated with significantly more uniform folliculogenesis and more effective steroidogenesis than the one using hMG. In addition, the hFSH protocol showed a trend toward more oocytes per laparoscopy and more embryos per transfer than the hMG group, although the difference was not statistically significant. More oocytes in the hMG group were classified as immature when compared with the hFSH group (P less than 0.05). Pregnancy rates in both groups were not significantly different. An allergic drug reaction that occurred in one patient on the hFSH protocol is the first such reaction reported with hFSH in the literature. The hFSH protocol is associated with a trend toward parameters that correlate with improved success rates in the IVF-ET program.

View details for Web of Science ID A1987K012300015

View details for PubMedID 3114011