PRESSURE, BIOCHEMICAL, AND CULTURE CHARACTERISTICS OF CSF ASSOCIATED WITH THE INUTERO DRAINAGE OF VARIOUS FETAL CNS DEFECTS AMERICAN JOURNAL OF MEDICAL GENETICS SIMPSON, G. F., Edwards, M. S., Callen, P., FILLY, R. F., Anderson, R. L., Golbus, M. S. 1988; 29 (2): 343-351

Abstract

An attempt has been made to begin delineation of the in utero dynamics of fetal intracranial fluid in the presence of brain malformations. In a series of patients with fetal CNS defects, cephalocentesis was performed at the time of therapeutic abortion or to facilitate vaginal delivery. Intracranial CSF pressures and volumes were quite variable. There did not appear to be any discernible correlation between the type of lesion and the intracranial pressure. Fetal CSF glucose levels were moderately depressed and protein concentrations were very high. Neither virus nor bacteria were cultured from fetal CSF or amniotic fluid of any patients in this series.

View details for Web of Science ID A1988M257600012

View details for PubMedID 3354605