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BACLOFEN TRIAL IN 6 MYOTONIC-DYSTROPHY PATIENTS ACTA NEUROLOGICA SCANDINAVICA Guilleminault, C., FLAGG, W. H., COBURN, S. C., Dement, W. C. 1978; 57 (3): 232-238

Abstract

Six young adult patients with grade I myotonic dystrophy and a complaint of daytime somnolence underwent 36-hour polygraphic monitoring, dynamometric and electromyographic studies before and under baclofen (60 mg/daily). Patients with the most severe daytime sleepiness had pathologic Sleep Apnea Indexes. After 6 weeks' ingestion of baclofen, no subjective or objective effect on patient symptomatology was found.

View details for Web of Science ID A1978FB08300004

View details for PubMedID 352086