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INCREASED INCIDENCE OF ACUTE NONLYMPHOCYTIC LEUKEMIA FOLLOWING THERAPY IN PATIENTS WITH SMALL CELL-CARCINOMA OF THE LUNG JOURNAL OF CLINICAL ONCOLOGY CHAK, L. Y., Sikic, B. I., TUCKER, M. A., Horns, R. C., Cox, R. S. 1984; 2 (5): 385-390

Abstract

A group of 158 patients with small cell carcinoma of the lung were followed for 174.5 person-years of observation to determine the risk of acute leukemia. Three cases of acute nonlymphocytic leukemia were observed at 2.3, 2.7, and 3.0 years. The relative risk of developing leukemia was 316 (95% confidence limit, 76-818) and the actuarial risk was 25% +/- 13% at 3.1 years. The relative risk for leukemia was significantly increased in these patients (p less than 0.0001).

View details for Web of Science ID A1984SS13800006

View details for PubMedID 6327924