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CUTANEOUS LYMPHOBLASTIC LYMPHOMA WITH PRE-B MARKERS BLOOD Link, M. P., Roper, M., Dorfman, R. F., Crist, W. M., COOPER, M. D., Levy, R. 1983; 61 (5): 838-841

Abstract

Two children with cutaneous convoluted lymphoblastic lymphoma are reported. Malignant cells from both patients contained cytoplasmic Mu heavy chains characteristic of pre-B-cells and expressed CALLA and la antigens as well. Most cases of convoluted lymphoblastic lymphoma are T-cell-derived neoplasms. The non-T, non-B phenotype found in these two children demonstrates that histology does not necessarily predict immunophenotype. The association of the pre-B phenotype with cutaneous lymphoma has not been previously reported, but may represent a unique clinical-histopathologic-immunologic entity that occurs in young children.

View details for Web of Science ID A1983QN28600003

View details for PubMedID 6600948