Isolated meningeal vasculopathy associated with Clostridium septicum infection NEUROLOGY Crowley, R. S., Lembke, A., Horoupian, D. S. 1997; 48 (1): 265-267


A 28-year-old patient with acute lymphoblastic leukemia and neutropenia developed necrotizing enterocolitis and Clostridium septicum bacteremia, followed by rhabdomyolysis, skin rash, and acute neurologic changes. Numerous cortical leptomeningeal enhancements were present on head MRI. Meningeal and brain biopsy showed segmental, full-thickness lysis of smooth muscle cells of medium-sized meningeal vessels with overall preservation of the structure of the vessel wall.

View details for Web of Science ID A1997WC67600049

View details for PubMedID 9008531