Antigen-independent determinants of graft survival in living-related kidney transplantation Symposium on Progression of Renal Disease - Clinical Patterns, Therapeutic Options and What We Have Learned from Clinical Trials Chertow, G. M., BRENNER, B. M., Mori, M., Mackenzie, H. S., Milford, E. L. NATURE PUBLISHING GROUP. 1997: S84–S86


We used the United Network of Organ Sharing database to define the antigen independent risk factors which contributed to the survival of 8,582 kidney transplants performed in the U.S. between October 1987 and December 1991, using multivariable regression techniques. In this analysis, death with a functioning graft was censored. The risk ratio for graft loss was high when recipients were African-American or had high body surface area, or when donors were older or female. The analysis shows that antigen independent factors that are associated with lower donor kidney mass or increased recipient size play a significant role in living donor kidney transplant loss, as they do in cadaver kidney transplantation.

View details for Web of Science ID A1997YJ60500022

View details for PubMedID 9407430