Reduction of cyclosporine dosage with ketoconazole in a patient with birdshot retinochoroidopathy AMERICAN JOURNAL OF OPHTHALMOLOGY Silverstein, B. E., Wong, I. G. 1998; 125 (1): 106-108

Abstract

To report the successful reduction of cyclosporine dosage with adjunctive ketoconazole in a patient with birdshot retinochoriodopathy.Case report.A 55-year-old woman treated with cyclosporine for birdshot retinochoroidopathy had ketoconazole (200 mg/day) added to her medical regimen. Her cyclosporine dosage was reduced to 40 mg per day from 200 mg per day, an 80% reduction. No toxic effect was observed during 12 months of follow-up nor was there progression of the birdshot retinochoroidopathy.Cyclosporine dosage may be reduced considerably in patients with uveitis who use adjunctive ketoconazole. The regimen appears to be safe and efficacious.

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View details for PubMedID 9437325