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Sex-based differences in the effect of intra-arterial treatment of stroke - Analysis of the PROACT-2 study

Sex-based differences in the effect of intra-arterial treatment of stroke - Analysis of the PROACT-2 study STROKE Hill, M. D., Kent, D. M., Hinchey, J., Rowley, H., Buchan, A. M., Wechsler, L. R., Higashida, R. T., Fischbein, N. J., Dillon, W. P., Gent, M., Firszt, C. M., Schulz, G. A., Furlan, A. J. 2006; 37 (9): 2322-2325

Abstract

Sex influences outcome after intravenous thrombolysis. In a combined analysis of the tissue plasminogen activator clinical trials, a sex-by-treatment interaction was observed. We sought to confirm that observation in an independent data set.Data were from the Pro-Urokinase for Acute Cerebral Thromboembolism-2 (PROACT-2) trial. Baseline factors were compared by sex. The primary outcome was an assessment of a sex-by-treatment interaction term within a logistic regression model, using a modified Rankin Scale score

View details for DOI 10.1161/01.STR.0000237060.21472.47

View details for Web of Science ID 000241715900036

View details for PubMedID 16888269